I’m not 100% sure — I’m just guessing based on the thread around Cyberpunk blocking the virtual input (Steam Controller mouse input) while the VorpX emulated mouse still worked — so they are obviously different somehow.
If I play the game normally with the Steam Controller or DualShock 4 (gamepad + mouse input on the gyro and the hex edit from Reddit) the UI doesn’t flicker, but VorpX still does (since the game somehow things the VorpX mouse is a hardware device).
Edit: More info here https://www.reddit.com/r/cyberpunkgame/comments/kamugy/cant_play_cyberpunk_2077_as_a_disabled_person/
This is a bug – someone on Reddit was able to find a fix and I can confirm it works. https://www.reddit.com/r/cyberpunkgame/comments/kb73fr/fix_for_virtual_input_not_working/
Unfortunately VorpX actually DOESN’T use virtual input so the UI keeps flipping between controller and keyboard prompts.