That sounds rather odd, never heard of that before. A reinstall might make sense.
If you have Windows system restore points enabled, it’s probably also a good idea to go back to a restore point from before the issue occured. That may save you some trouble shooting.
I was due for a clean install anyway, so I erased my hard drive, and reinstalled Windows 10, Steam, SteamVR, latest Nvidia drivers, and VorpX. The first time I opened VorpX, the configuration window was fine. But the first time I opened it from inside the SteamVR Desktop, it was blank again!
Could this be a GPU driver thing? I switched the Windows Desktop resolution, but the window stayed blank.
Any ideas?