vorpX 21.1.0 had a bug that could cause similar behavior, but that should be fixed now with the 21.1.1 release from yesterday.
If you still experience this with 21.1.1, try to set the Headset Sync option in the vorpX menu to ‘Safe’, which will cost some FPS, but gives the GPU a bit more leeway. Also FluidSync to ‘On’ is worth a shot, that should be the case for Cyberpunk anyway though.
If none of the above helps, there might be something getting in the way. If you happen to have any GPU/CPU tools installed, try to disable/uninstall them. Such tools tend to also hook into games similar to vorpX, which may cause conflicts. The same is true for some chat apps (Discord, Skype etc.) and generally everything that can show notifications in games.