When you change HUD scale, on some games at least focus of mouse pointer gets wrong when pointing mouse over 3D scene, hud works correctly but games detects mouse pointer over their old position (this is not where vorpx pointer seems to be).
Unfortunately there are some games where for this or that reason the cursor may have different coordinates than a scaled HUD. Switching to EdgePeek while using menus helps in such cases. In EdgePeek mode HUDs and menus aren’t scaled.