Hey. Just to chime in – purchased the software just yesterday and I seem to have the same problem.
I’ve tested two games thus far – bioshock and cloudpunk.
In Bioshock, pressing CTRL+ALT+SHIFT to close the intro message doesn’t work, neither does Delete or any other button press. Pressing something like ALT+L or ALT+V does.
In Cloudpunk, nothing works except EdgePeek.
At this point I’ve disabled and closed pretty much all there is and I don’t know what else to do.