First and foremost: use purchased games. Who knows how your cracks work and what they do. Some may for example use different .exe names than the legit game or call some other .exe that vorpX is unaware of. Both cases would prevent vorpX from working correctly since it would not be able to recognize a game. And there are almost certainly more potential issues a crack could cause that I’m unaware of.
That said:
Please try a full factory reset in the config app. There is no cloud profile required for Fallout 4.
Apart from that in case of hooking issues most likely there is a conflict with some other program. In the vast majority of cases that is the problem. You can find more detailed information on the matter in the trouble shooting post on top of this sub forum.
Also checking the ‘Alternative Hooking’ option in the config app is worth a shot. Caveat: even if it helps with a particular game, don’t forget to switch back. It’s not better per se, and some games definitely require the defauzlt method.