This happens with INVISIBLE INC. (vorpX hooked).
It probably ain´t that much of an issue since it´s an old game not really demanding high hardware so i can play it with desktop-viewer probably.
But this seems to be some vorpX related issue nonetheless and before this happens with other games too, i am better asking!
So well, once the game starts, mouse-cursor moves up to the left corner and stays there. Can move the mouse as i want but mouse-cursor doesn´t.
This also only happens with vorpX running/hooked, the game without vorpX starts fine without that issue.