Before the official profile for Jedi: Fallen Order launched I was able to use VORPX without issue using a cloud profile. Since the official release, the game closes on startup every time and I have yet to be able to get the game to work properly with this software. The easiest way to be able to fix similar problems would be to allow an advanced option to let users use cloud profiles to help alleviate certain problems.
There is no difference between official profiles and user profiles in regard to the hooking process. Almost certainly a coincidence that this happens just now for you.
Try to disable the Origin overlay in the Origin options. Shouldn’t be necessary, but may help. Also enabling alternative hooking in the config app may be worth a shot. caveat: switch back to default hooking later even if that helps, some games require default hooking.