Unfortunately that can happen with some av programs with each new vorpX version. Quite annoying. Ideally please report the issue as false positive to your av vendor, so they can fix this. You can also let me know which av program you are using. Then I can report it to them.
BTW: My personal recommendation would be to use Windows Defender, which has become quite good over time and isn’t as overzealous as some of the others. There only was one issue with Windows Defender in over three years now.
I have also been having this issue. Vorpx seems to be running on it’s own but Vorpconfig just closes with that error. I do not have any virus software installed, disabled Windows Defender and reinstalled Framework 3.5. Killed any possible task in the background. Nothing seems to work.
I would really like to run SkyrimSE prelim profiles but I can’t load them without the config. Not sure what else to try. Is there another way to install the profiles without the vorpconfig? All the vorpx settings seem to work in inside a game but without the SkyrimSE profile I’m not getting any 3D support and it looks bad.
What else could I try to get the config to work? Also started as admin and that doesn’t work either. Seems so weird to me that vorpx works but the config does not.
I also sent email to vorpx support with no response. I bought it to use specifically with Fallout 4 and SkyrimSE. Fallout 4 at least had a profile installed so that’s working.