After learning how to go the injector route to install ENB, I was able to get it to work with Skyrim. Some helpful vids on youtube that explain how to set it up. It does hit the performance harder this way, but at least it works.
Generally Sweetfx is less performance hungry with games, but I’m not having luck using it with Vorpx. I’ve read that some can inject it through RadeonPro (witch is actually how I add sweetfx to my games normally), but I’ve had no luck getting Vorpx to agree with Radeonpro. Only if I disable API monitoring will Vorpx let me launch a game with Rpro. But doing that disables the sweetfx.
So my question to anyone here is how they got RadeonPro and sweetfx to work with Vorpx. Cheers.