When I launch The Talos Principle vorpx does not recognize the game. I can get it to if I change a setting (does not matter which one) in the graphics settings after I have started the game with vorpx running but when I do this the colors are all messed up.
You have to enable multisample antialising in the game’s graphics options. Should be on per default, but maybe you switched it off accidentally. I would suggest the low (2x) setting for performance reasons. The game is a first class resource hog.
Apart from some minor color corruption in the menu background it should work quite well this way. Tested with the latest Steam version, which was released today I think.