You don’t have to care about that. I did :). Two or more profiles in the local list with the same .exe assigned cannot occur.
If you import settings for an official profile, such a collision is impossible by design since user settings for official profiles do not contain the .exe assignment in the first place.
If you import a full user profile that has the same .exe assigned than an existing user profile in your local list, the .exe is removed from the prior profile on import. IIRC vorpX should show a message in that case, but I’m not 100% sure ATM, mght also happen silently.