Vulkan definitely won’t work, OpenGL still works here. Please note though that the game is not officially supported, OpenGL support in vorpX only fully covers older OpenGL versions up until about Doom 3/Quake 4.
However, if it doesn’t hook at all in OpenGL mode, please check for the ‘usual suspects’ in regard to hooking issues: virus scanners, GPU/CPU utilities, messengers, game recording/streaming apps, generally everything that can show notifications in games.
If you haven’t done so already, trying the alternative hooking method in the config app is also worth a shot. Caveat: the alternative method is not meant for general use. Only activate it in case of issues with a specific game.