Unless there is a serious file system error on your hard drive (unlikely), this sounds a lot like some annoying antivirus problem. If you happen to use anything else than Windows Defender, try to disable it and see whether that helps. Windows Defender should not cause any problems.
BTW: There isn’t really any need for (usually more invasive) third party AV software on Windows 10. Windows Defender is more than good enough for several years now, so if you use something else, you might even want to consider removing it entirely. Windows Defender means less hassle and annoyances with the same level of protection.