I’m having the exact same problem. Every since I installed Vorpx, Steam games that are expected to hook with Vorpx crash at the launcher or barely into the game.
This includes:
Bioshock Infinite
Skyrim
Portal 2
Other steam games work fine (i.e. XCOM, Dawn of War 2 – anything not advertised as compatible with Vorpx). I’ve completely uninstalled Vorpx and I still get the crashing. Anyone have any ideas?