you can. i just got it working on quest 2 and vd yesterday. not sure what i did to fix it as it took a while and maybe 10 tries to get it “working” and switching the setting to steam vr was the last thing i did. be sure you have the game profile already before starting the game. when you start the game from steam desktop it should say something about opening in a virtual environment and should also be a prompt for the game.exe. vorpx does its thing automatically (running) if its a compatible game like instead of opening it as an app then opening something from it. that concept is probably what took me so long to get it running