Games do all kinds of inexplicable crap when you alt-tab away, if you even can – some games simply won’t let you, others crash, blah blah blah. Some work flawlessly with vorpx and others are a pain in the arse. As far as Vorpx is concerned, you’re essentially asking it to drop it’s hook and reacquire it because you decided to check your email mid-game.
If there’s absolutely something that you need to do after starting a game with vorpx, set a windows 10 shortcut, use antimicro to map some keystrokes to your controller, or something other than alt-tabbing if the game is misbehaving in that area. It’s almost always the game, not vorpx, that makes alt-tabbing an issue.