I just gave Ori and the Blind Forest a try today with the Vive.
vorpX had no trouble hooking into the game. But I was only able to get Virtual Cinema mode to work with it.
My steps:
1 start steam
2 start steam vr
3 start vorpX
4 launch game from steam
5 put on headset and bring up vorpX settings
6 set Cinema mode
7 set Lock Head Tracking on
8 change vorpX and game settings to your preferences.
Geometry 3D mode: not supported
Z-Normal 3D mode: not supported
Virtual Cinema mode: supported
On the Vive the game looked very nice and played very well using keyboard/mouse and 360 controller; Some very minor screen door effects on Ori’s body when perfectly still. all and all no good reason to, or not to, play the game in or out of VR.