I managed to get MassEffect 3 LE working.
You have to trick the launcher, just do that:
1) go in installation folder
2) Go in GAME\ME3\Binaries\Win64 and rename MassEffect3.exe into MassEffect1.exe
3) Go back in GAME folder
4) Rename ME1 into ME1_
5) Rename ME3 into ME1
6) Launch MassEffect 1 from the Launcher
Enjoy ME3 into VORPX
^^