Hey surrealeus and anyone else getting frequent crashes, this worked for me based on this article (item 15):
http://www.gamepur.com/guide/24760-skyrim-special-edition-error-fix-black-screen-startup-transfer-old-saves.html
Had to disable the Touch Keyboard service on Windows 10. The crashes would be unrelated to what I was doing, even if I was in the pause menu in game.
For reference:
“You must Disable the “Touch Keyboard and Handwriting Panel Service” service. Click your windows button, type in “services” and select that app it finds, which should be called “Services”. In services, scroll down until you find the “Touch Keyboard and Handwriting Panel Service”.
Double click the service name.
For “startup type” select “disabled”
Then click the stop button.
”
Hope this helps, and hope I can figure out good profile settings that work for this. :)