I have this EXACT issue. Had it on 2 machines and never fixed it. I’m not sure if it’s hardware as this used also happen on my GTX 770 but I have AMD hardware and have this issue. I’m running a DK2 so I’m not sure if it’s dependant on that
I once got it working by leaving the game on for awhile and trying again but most the time it completely crashes my system forcing a reboot. I can play without direct VR but the experience is awful. I also have an issue with the controller which I read is also fixed by directVR scanner.
I got the controller working perfectly with New Vegas with mapping support and head tracking but playing that makes me want to start Fallout 4 again.
Until ralf posts back (if he has the time) the best thing to do is change the FOV to 120 in the INI settings and lower your graphics. That helped me at least get the scanner to not crash my system.
We’ll have to ask Ralf if he knows anything about this, id love his input, it’s always valued