As far as mods are concerned the best rule of thumb is avoiding anything that hooks into the graphics pipeline as this tend to cause conflicts with vorpX (which does the same). Post FX mods, shader mods etc. typically fall into this category. A good indicator of whether a mod has the potential to cause trouble is whether it puts any DLL in the game folder, which usually means that the mod hooks into the game similar to vorpX.
Also camera mods are to be avoided in games where vorpX handles the FOV or applies head tracking via its memory scanner function.
Most other mods usually work, but of course there is no guarantee for that. If in doubt, first try without mods, then add mods in batches to easily find an offending one.